NL-OMON52015招募中不适用
MOODSTRATIFICATION IMMUNOSTRATA Groningen Premature immune ageing and spinning therapy in mood disorders - IMMUNOSTRATA Groningen
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 132
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •- A depressive episode in the course of unipolar or bipolar disorder with a
- •HDRS-17 score >13 - Meets DSM criteria for MDD or BD established by MINI
- •- Age 18-65 years
- •- Already on an anti-depressant and/or mood stabilizer apparently without
- •success - Signed informed consent, able to understand, speak and write the
- •national language
- •Healthy ontrols
- •- No history of psychiatric disorders
- •- Age 18-65 years
- •- Signed informed consent, able to understand, speak and write the national
排除标准
- •- Use of beta blockers or other medication affecting hearth frequency (patients)
- •- Abnormalities on ECG (other than normal sinus rhythm) (patients)
- •- Chronic use of anti-inflammatory drugs
- •- Existing cancer or history of cancer in the last 5 years (except skin
- •epidermoid cancer or in-situ cervix cancer)
- •- Existing or planned pregnancy or lactation
- •- Schizoaffective disorders, schizophrenia
- •- Immediate risk for suicidal behavior (3 on HamD-17 rating scale
- •- Known current uncontrolled systemic disease (e.g. LE, RA).
- •- Known major uncontrolled metabolic disorder (e.g. diabetes, hyper- or
- •hypothyroidism, Cushing disease of Addison disease).
- •- Known other significant uncontrolled somatic/organic/neurological disorder,
- •such as or diabetes or stroke which may affect mood.
- •- Current or recent (last 4 weeks) use of somatic medication which may affect
- •mood or the immune system (e.g. corticoids, anti-inflammatory drugs, immune
- •suppressive drugs).
- •- Participation in a study of an investigational drug or device concomitantly
- •or within 30 days prior to this study
- •- Patients thought to be unreliable or incapable of complying with the
- •requirements of the protocol
- •- Patient is relative of, or staff directly reporting to the investigator
研究者
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