Contributions of the supplementary motor area and the pre-motor cortex to skilled sequential action: a TMS study.

Completed

• Conditions: geen aandoeningen; n.v.t.

• Registration Number: NL-OMON37597
• Lead Sponsor: niversiteit Twente

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 48

Inclusion Criteria

Subjects should be 18 years or older (capable of giving informed consent), and right handed (as indicated by the Annett Handedness Inventory).

Exclusion Criteria

Subjects are excluded if they:
- have a personal history of epilepsy;
- have a lesion in the brain, be it vascular, traumatic, tumoral, infectious or metabolic;
- have hearing problems;
- might be pregnant;
- have metal objects in their brain/skull;
- have a cochlear implant, implanted brain electrodes or pacemaker;
- suffer from a severe medical condition;
- use medications that form a relative hazard for application of TMS due to a seizure threshold lowering potential;
- had spinal surgery, or have drains in their spinal cord or ventricles;
- have used any illegal drugs in the last month.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter is the difference in response time on a motor<br /><br>sequencing task between subjects in three rTMS conditions (SMA, PMC, sham).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>We will measure the number of correctly performed sequences in each condition<br /><br>for all subjects. Also, subjects will be asked to recall the sequences that<br /><br>they have performed during the experiment and recognize these sequence from a<br /><br>list of 12 alternatives.</p><br>