St. John's Wort Vs. Placebo in Obsessive-Compulsive Disorder.

Phase 2

Completed

• Conditions: Obsessive Compulsive Disorder

• Registration Number: NCT00035438
• Lead Sponsor: National Center for Complementary and Integrative Health (NCCIH)

Brief Summary

The purpose of this study is to determine the effectiveness of St. John's Wort as compared to placebo (an inactive substance) in the treatment of outpatients with obsessive compulsive disorder.

Detailed Description

The objective of the proposed study is to assess the efficacy of the herbal St. John's Wort (SJW) in the treatment of symptoms of obsessive-compulsive disorder (OCD). The approach is to conduct a 12-week, randomized, double blind, placebo controlled, parallel group pilot trial with 30 subjects in each of two arms. The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) will be the primary measure for evaluating OCD. An intention-to-treat analysis will be done to compare the two arms.

Study Timeline

• Study Start: 2002-05
• Study First Submitted: 2002-05-03
• Study First Submitted QC: 2002-05-03
• Study First Posted: 2002-05-06
• Study Completion: 2003-09
• Status Verified: 2006-08
• Last Update Submitted: 2006-08-03
• Last Update Posted: 2006-08-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Trial Locations

Locations (2)

University of Oklahoma Health Science Center; 🇺🇸 Oklahoma City, Oklahoma, United States

Dean Foundation; 🇺🇸 Madison, Wisconsin, United States