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Development of a Tailored Smoking Cessation Program for Individuals With HIV Infection in Washington, D.C.

Not Applicable
Completed
Conditions
Tobacco Smoking
Interventions
Behavioral: Standard of Care
Behavioral: Tailored behavioral counseling
Registration Number
NCT04594109
Lead Sponsor
Colorado State University
Brief Summary

Morbidity and mortality from smoking-related diseases among people living with HIV (PLWH) in the U.S. surpasses that due to HIV itself. Conventional smoking cessation treatments have not demonstrated strong efficacy among PLWH. The investigators conducted a pilot randomized controlled trial (RCT) to evaluate a tailored smoking cessation intervention based on the minority stress model, hypothesizing that behavioral counseling through this lens would enhance cessation. The investigators compared standard of care counseling (SOC) to a tailored intervention (TI) including one face-to-face counseling session incorporating cognitive behavioral therapy to build resilience, and 30 days of 2-way text messaging.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
25
Inclusion Criteria
  • ≥18 years of age
  • report being HIV-infected
  • be a resident of the Washington, D.C. area
  • current, daily smokers of tobacco
  • have a confirmed smoking status of 6 parts per million (ppm) or more by using an exhaled carbon monoxide breath monitor
  • agree to participate
  • be willing to set a quit date within 7 days of baseline assessment.
Exclusion Criteria
  • are currently using smokeless tobacco or electronic cigarettes at least every day
  • are currently using nicotine replacement therapy or other smoking cessation treatment
  • report being HIV-uninfected
  • report having heart disease or high blood pressure not controlled by medication
  • are currently in an alcohol treatment program
  • are pregnant (exclusion items 4-6 are contraindications of nicotine replacement therapy, which will be provided)
  • do not have a primary care provider or HIV care provider to refer to in the event of an adverse reaction to nicotine replacement therapy.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Standard of CareStandard of CareOne-time standard of care in-person behavioral counseling lasting approximately one hour, plus a 30-day supply of nicotine replacement therapy consisting of nicotine patches and nicotine gum (dosage according to current smoking intensity according to manufacturers instructions). The standard of care behavioral counseling was adapted from the current U.S. clinical practice guidelines.
Tailored CounselingTailored behavioral counselingParticipants in the intervention arm were provided a one-time tailored cognitive-behavioral therapy in-person cessation counseling intervention lasting approximately one hour, a 30-day supply of nicotine replacement therapy (consisting of nicotine patches and nicotine gum; dosage according to current smoking intensity according to manufacturers instructions), and a tailored bi-directional text messaging program delivering two messages per day for four weeks. The TI session was adapted from the clinical practice guidelines to include behavioral elements rooted in the minority stress model. The intervention used addressed issues of stress related to HIV stigma, minority status and socioeconomic condition.
Primary Outcome Measures
NameTimeMethod
Smoking Abstinence30 day follow-up

7-day point prevalence plus exhaled breath carbon monoxide \< 7 parts per million (ppm)

Secondary Outcome Measures
NameTimeMethod
Cigarettes per day30 day follow-up

Number of cigarettes smoked per day

Self-efficacy30 day follow-up

Self-efficacy for smoking abstinence

Exhaled breath carbon monoxide30 day follow-up

Exhaled breath carbon monoxide in parts per million (ppm)

Trial Locations

Locations (1)

Truth Initiative

🇺🇸

Washington, District of Columbia, United States

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