Prospective Study of the Impact of Systemic Corticosteroid Use on Measures of Sleep Disordered Breathing

Completed

• Conditions: Sleep Apnea
• Interventions: Other: sleep study

• Registration Number: NCT01228695
• Lead Sponsor: Rambam Health Care Campus

Brief Summary

Weight gain is both a significant risk factor for obstructive sleep apnea and a side-effect of long-term systemic steroids therapy.

This study aimed to investigate the impact of long-term systemic steroid treatment on sleep apnea.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-01
• Primary Completion: 2010-01
• Study Completion: 2010-01
• Status Verified: 2010-02
• Study First Submitted: 2010-10-21
• Study First Submitted QC: 2010-10-25
• Last Update Submitted: 2010-10-25
• Study First Posted: 2010-10-26
• Last Update Posted: 2010-10-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• For inclusion, a scheduled therapy with a minimum daily dose of 10 mg prednisone (or equivalent) for at least 3 months was required

Exclusion Criteria

• Patients younger than 18 years and those with known sleep apnea or other forms of sleep-disordered breathing were excluded

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
steroid treatment	sleep study	-

Primary Outcome Measures

Name	Time	Method
apnea-hypopnea index	3 months

Secondary Outcome Measures

Name	Time	Method
sleep study variables	3 months	apnea-hypopnea interval desaturation at the end of apnea interval snoring intensity

Trial Locations

Locations (1)

Rambam health care campus; 🇮🇱 Haifa, Israel