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Expanded Access to RXDX-105 for Cancers With RET Alterations

Conditions
Cancers With RET Alterations
Registration Number
NCT03052569
Lead Sponsor
Hoffmann-La Roche
Brief Summary

Expanded access to RXDX-105 will be given to patients with cancers harboring RET alterations who have not received TKIs that target RET alterations, who do not qualify for participation in, or who are otherwise unable to access, an ongoing clinical trial for RXDX-105.

Detailed Description

Not available

Recruitment & Eligibility

Status
NO_LONGER_AVAILABLE
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Diagnosis of advanced cancer with RET alterations
  • Unable to participate in an ongoing RXDX-105 clinical trial
  • Willing and able to provide written, signed informed consent
  • Medically suitable for treatment with RXDX-105
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Exclusion Criteria
  • Prior treatment with a TKI that has activity against RET alterations
  • Currently enrolled in an ongoing clinical study with any other investigational agent
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Study & Design

Study Type
EXPANDED_ACCESS
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Www.Ignyta.Com

🇺🇸

San Diego, California, United States

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