Pulmonary Arterial Hypertension in Systemic Sclerosis
- Conditions
- Systemic SclerosisPulmonary Arterial Hypertension
- Registration Number
- NCT00617487
- Lead Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
- Brief Summary
The purpose of this study is to evaluate the role of stress echocardiography, compared to standard echocardiography in the early identification of pulmonary arterial hypertension in systemic sclerosis. To evaluate the role of BNP in this setting.To analyze data recorded with respect to the parameters commonly used for SSc evaluation (eg thorax HRCT, pulmonary function tests + DLCO, nailfold capillaroscopy, etc); these parameters are available starting for 1999.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
- Patients with systemic sclerosis according to LeRoy criteria
Exclusion Criteria
- Pregnancy
- Significant valvular disease
- Low left ventricular function upon echocardiography (ejection fraction<55%)
- History of atrial fibrillation, myocardial infarction, pulmonary thromboembolisms, neoplasia or severe hepatic disease.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
IRCCS Foundation Policlinico S. Matteo
🇮🇹Pavia, PV, Italy
IRCCS Policlinico S. Matteo
🇮🇹Pavia, PV, Italy