EUCTR2008-006080-36-GB
Active, not recruiting
Not Applicable
Analgesic efficacy of ultrasound guided transversus abdominis plane block as part of a multimodal analgesic regime for post elective caesarean section pain – a comparative double-blinded placebo controlled trial using plain bupivacaine, bupivacaine with adrenaline and bupivacaine with dexamethasone. - Do adjuncts in TAP blocks prolong analgesia post caesarean section?
ConditionsThis study is aimed at improving pain relief for women undergoing a planned caesarean section. Current pain relieving regimes are not ideal and often lead to women experiencing considerable pain after their operation. We would like to use local anaesthetic blocks (transversus abdominis plane blocks) to improve their pain relief. Adjuncts to the local anaesthetic may prolong and improve the quality of the analgesia.MedDRA version: 9.1Level: LLTClassification code 10036276Term: Postoperative analgesiaMedDRA version: 9.1Level: LLTClassification code 10024977Term: Lower segment Caesarean section
DrugsMarcain 0.25%
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- This study is aimed at improving pain relief for women undergoing a planned caesarean section. Current pain relieving regimes are not ideal and often lead to women experiencing considerable pain after their operation. We would like to use local anaesthetic blocks (transversus abdominis plane blocks) to improve their pain relief. Adjuncts to the local anaesthetic may prolong and improve the quality of the analgesia.
- Sponsor
- Portsmouth Hospitals NHS Trust
- Status
- Active, not recruiting
- Last Updated
- 10 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\)women undergoing elective caesarean section at St Mary’s Hospital who are able to receive the standard anaesthetic and analgesic regime
- •2\)women who are fit and well or who have only mild to moderate functional disability ( ASA 1 or 2\)
- •3\)women aged between 18 and 50 years of age
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
- •F.1\.3 Elderly (\>\=65 years) no
- •F.1\.3\.1 Number of subjects for this age range
Exclusion Criteria
- •1\)women unable to receive the standard regime ie severe pre\-eclampsia, coagulopathy, local anaesthetic allergy, non\-steroidal anti\-inflammatory drug intolerance
- •2\)patients with an early pregnancy (booking) body mass index of \>40
- •3\)patients who are immunocompromised
- •4\)patients weighing \<50kg
- •5\)patients with diabetes requiring insulin
- •6\)patients taking any drugs with analgesic activity
- •7\)women at the extremes of reproductive age: less than 18 years and greater than 50 years
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not yet recruiting
Phase 4
ltrasound guided TAP block in post-LSCS patient under spinal anaesthesia for pain reliefHealth Condition 1: O94- Sequelae of complication of pregnancy, childbirth, and the puerperiumCTRI/2019/03/018080Baroda Medical College
Recruiting
Phase 2
To test the pain relief provided by Transversus Abdominis Plane (TAP) Block under ultrasound guidance in Adult patients with Gall stone disease undergoing Single Incision Laparoscopic Cholecystectomy (SILC)surgery.Health Condition 1: null- Patients undergoing Single Incision Laparoscopic Cholecystectomy (SILC) for Gall Stone DiseaseCTRI/2014/09/004942All India Institute Of Medical Sciences63
Completed
Not Applicable
The analgesic efficacy of ultrasound guided transversus abdominis plane (TAP) block after laparascopic appendicectomy in children: a prospective randomised trialPost-operative pain after laparscopic appendicectomyAnaesthesiology - AnaestheticsACTRN12608000314325Dr David Sandeman90
Completed
Phase 2
Pilot Trial of Transversus Abdominis Plane Ropivacaine Infusions following Abdominal SurgeryACTRN12608000291381Western Health20
Not yet recruiting
Phase 2
The Analgesic Efficacy of Ultrasound-Guided Transversus Abdominis Plane Blocks after Abdominal SurgeryAnalgesia in patients undergoing abdominal surgeryAnaesthesiology - AnaestheticsACTRN12608000297325Dr Elizabeth Hessian52