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An Observational Study of OZURDEX® in Diabetic Macular Edema (DME)

Completed
Conditions
Macular Edema
Interventions
Registration Number
NCT02188173
Lead Sponsor
Allergan
Brief Summary

This is a study of OZURDEX® use in clinical practice in patients with diabetic macular edema (DME).

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
200
Inclusion Criteria
  • Diagnosis of DME in at least one eye treated OZURDEX® per clinical practice
Exclusion Criteria
  • None

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
dexamethasone 700 ㎍ intravitreal implantdexamethasone 700 ㎍ intravitreal implantPatients who receive dexamethasone 700 ㎍ (OZURDEX®) intravitreal implant treatment for Diabetic Macular Edema. All decisions regarding treatment are made at the sole discretion of the treating physician in accordance with their usual practices.
Primary Outcome Measures
NameTimeMethod
Maximum Change from Baseline in Best Corrected Visual Acuity (BCVA) in the Study EyeBaseline, 12 Months
Percentage of Patients with a BCVA Improvement of ≥15 Letters in the Study EyeBaseline, 12 Months
Average Change from Baseline in BCVA in the Study EyeBaseline, 12 Months
Secondary Outcome Measures
NameTimeMethod
Percentage of Patients with an Increase from Baseline of ≥2 Lines in BCVA in the Study EyeBaseline, 12 Months
Percentage of Patients with an Increase from Baseline of ≥3 Lines in BCVA in the Study EyeBaseline, 12 Months
Percentage of Patients with BCVA of 20/40 or Better in the Study EyeBaseline, 12 Months
Mean Number of Ozurdex Injections in the Study Eye12 Months
Mean Time Between Ozurdex Injections in the Study Eye12 Months
Change from Baseline in Central Retinal Subfield Thickness (CRT) in the Study EyeBaseline, 12 Months

Trial Locations

Locations (18)

Raj Maturi, MD PC

🇺🇸

Indianapolis, Indiana, United States

Texas Retina Associates, Arlington

🇺🇸

Arlington, Texas, United States

Bay Area Retina Associates

🇺🇸

Walnut Creek, California, United States

John-Kenyon American Eye Institute

🇺🇸

New Albany, Indiana, United States

Lifelong Vision Foundation

🇺🇸

Chesterfield, Missouri, United States

Long Island Vitreoretinal Consultants - Long Island Retina - Hauppauge

🇺🇸

Great Neck, New York, United States

Medical Center Ophthalmology Associates

🇺🇸

San Antonio, Texas, United States

Mid Atlantic Retina

🇺🇸

Philadelphia, Pennsylvania, United States

Valley Retina Institute, P.A.

🇺🇸

McAllen, Texas, United States

Associated Retinal Consultants, PC

🇺🇸

Traverse City, Michigan, United States

Associated Retina Consultants

🇺🇸

Royal Oak, Michigan, United States

New Jersey Retina

🇺🇸

New Brunswick, New Jersey, United States

Eyesight Ophthalmic Services

🇺🇸

Portsmouth, New Hampshire, United States

Illinois Retina Associates

🇺🇸

Harvey, Illinois, United States

Retinal Consultants of Phoenix

🇺🇸

Phoenix, Arizona, United States

West Coast Retina

🇺🇸

San Francisco, California, United States

Orange Co Retina Medical Group

🇺🇸

Santa Ana, California, United States

Colorado Retina Associates

🇺🇸

Denver, Colorado, United States

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