Brain Oxygenation During Cardiopulmonary Resuscitation - Observational Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Arterial oxygen partial pressure
研究概览
简要总结
The study is aimed to assess (a) the incidence of hyperoxia at the point of return of spontaneous circulation (ROSC) and (b) the role of arterial blood oxygen partial pressure to brain oxygenation during out-of-hospital cardiac arrest. 80 adult patients will be recruited in a physician staffed helicopter emergency medical services. Brain regional oxygen saturation and invasive blood pressure are monitored until hospital admission and arterial blood gases are analyzed immediately when the unit arrives to the patient and again at the time of ROSC.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •out-of-hospital cardiac arrest of presumed cardiac origin
- •resuscitation will be continued at least 5 minutes (if return of spontaneous circulation not achieved earlier) after arrival of physician team
排除标准
- •do-not-attempt-resuscitation (DNAR) order or withdrawal of treatment by prehospital critical care physician
- •return of spontaneous circulation achieved before physician-led critical team arrives
- •external cause for cardiac arrest (e.g. trauma, suffocation)
- •workload too high or environment too dangerous to perform study procedures
结局指标
主要结局
Arterial oxygen partial pressure
时间窗: 5-60 minutes
Arterial oxygen partial pressure at the time of return of spontaneous circulation (ROSC)
次要结局
- Forehead regional oxygen saturation during resuscitation(0-60 minutes)
研究者
Jouni Nurmi, MD
Consultant in Anaesthesia and Intensive Care Medicine
Helsinki University Central Hospital