Brain Oxygenation During Cardiopulmonary Resuscitation
- Conditions
- Cardiac Arrest, Out-Of-Hospital
- Registration Number
- NCT03464123
- Lead Sponsor
- Helsinki University Central Hospital
- Brief Summary
The study is aimed to assess (a) the incidence of hyperoxia at the point of return of spontaneous circulation (ROSC) and (b) the role of arterial blood oxygen partial pressure to brain oxygenation during out-of-hospital cardiac arrest. 80 adult patients will be recruited in a physician staffed helicopter emergency medical services. Brain regional oxygen saturation and invasive blood pressure are monitored until hospital admission and arterial blood gases are analyzed immediately when the unit arrives to the patient and again at the time of ROSC.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 80
- out-of-hospital cardiac arrest of presumed cardiac origin
- resuscitation will be continued at least 5 minutes (if return of spontaneous circulation not achieved earlier) after arrival of physician team
- do-not-attempt-resuscitation (DNAR) order or withdrawal of treatment by prehospital critical care physician
- return of spontaneous circulation achieved before physician-led critical team arrives
- external cause for cardiac arrest (e.g. trauma, suffocation)
- workload too high or environment too dangerous to perform study procedures
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Arterial oxygen partial pressure 5-60 minutes Arterial oxygen partial pressure at the time of return of spontaneous circulation (ROSC)
- Secondary Outcome Measures
Name Time Method Forehead regional oxygen saturation during resuscitation 0-60 minutes Oxygen saturation measured using near-infrared spectroscopy
Trial Locations
- Locations (1)
FinnHEMS 10, Emergency Medicine and Services, Helsinki University Hospital
🇫🇮Vantaa, Finland