Effects of Conjugated Linoleic Acid and Exercise on Body Fat Mass and Lipid Profiles Among Overweight Iranians After Weight Loss
- Conditions
- Diet and Nutrition Weight Loss
- Registration Number
- JPRN-UMIN000020284
- Lead Sponsor
- niversity Puta Malaysia
- Brief Summary
171 subjects completed their participation (Response Rate = 95%), and in comparison with the baseline body weight, Body Mass Index (BMI), Body Fat Mass (BFM), and waist to hip ratio of the CLA and CLA+E groups had a significant decrease (P < 0.05) with average BFM loss being 10.3% and 12% among CLA and CLA+E, respectively, compared to 2.7% among Control group. As for the biochemical analysis, the blood free fatty acid increased and high density lipoprotein decreased in CLA group which was an unfavorable effect of CLA supplementation. Although the supplementation alone appeared to have some non-desirable effects on the mentioned blood tests, this change did not occur among the exercise group. As a conclusion, supplementation with conjugated linoleic acid among overweight Iranians for 12 weeks reduced the BFM with some adverse effects on blood profiles which can be controlled through a moderate-intense exercise.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 180
Not provided
Pregnancy, nursing, history of hospitalization, or any former or current health related condition considered as the exclusion criteria.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Significant Change in Body Fat Mass (Baseline, and at 6 and 12 weeks after intervention commencement)
- Secondary Outcome Measures
Name Time Method Significant Change in Lipid Profiles (Baseline, and at 6 and 12 weeks after intervention commencement)