Pilot Program to Improve Statin Adherence and Lower Cholesterol in Older Adults
概览
- 阶段
- 1 期
- 干预措施
- 未指定
- 疾病 / 适应症
- Hypercholesterolemia
- 发起方
- University of Missouri-Columbia
- 入组人数
- 43
- 试验地点
- 1
- 主要终点
- Medication adherence
- 状态
- 已完成
- 最后更新
- 9年前
概览
简要总结
The purpose of this study is to pilot test a behavioral medication adherence (MA) intervention compared to control condition in older adults with low adherence to medication for hypercholesterolemia.
详细描述
This study will answer the following primary research question: 1. What is the estimated effect size of a behavioral MA intervention on MA rates in older adults who are poorly adherent to statin medications? The study will also explore the following secondary research questions: 2. What is the estimated effect size of a behavioral MA intervention on low-density lipoprotein cholesterol (LDL-C) levels in older adults? 3. What is the estimated effect size of a behavioral MA intervention on high-density lipoprotein cholesterol (HDL-C) levels in older adults? 4. What is the feasibility of successfully testing this intervention protocol in a population of older adults with low adherence to statin medications?
研究者
入排标准
入选标准
- •Age 60 or older at the time of study entry,
- •Take a once-daily prescription statin medication for ≥ 6 months with no changes to statin prescription for at least 30 days prior to study entry,
- •A score of ≤ 9 on the Short Blessed Test,
- •Participants must self-administer his or her own medications without prompts from any other person or device.
- •Baseline medication adherence rate of ≤ 90%.
- •Participants agree to complete all study contacts and measurements, including the use of a special medication bottle with a Medication Event Monitoring System (MEMS) cap for the duration of the study.
- •Able to open and close MEMS caps.
排除标准
- •Participant's medications are managed by someone other than the participant
- •Participant is unable or unwilling to use MEMS caps.
结局指标
主要结局
Medication adherence
时间窗: 6 months
次要结局
- Serum cholesterol(6 months)