Medication Adherence in Rheumatic Diseases

Not Applicable

Completed

• Conditions: Chronic Rheumatic Diseases

• Registration Number: NCT06018350
• Lead Sponsor: Duke University

Brief Summary

The investigators will pilot test a clinician-led intervention to improve medication adherence in general rheumatology clinic across a spectrum of rheumatic diseases. The study will assess feasibility, acceptability, and fidelity, and explore signal for improved medication adherence.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-08-25
• Study First Submitted QC: 2023-08-25
• Study First Posted: 2023-08-30
• Study Start: 2024-02-02
• Primary Completion: 2024-06-05
• Study Completion: 2024-06-22
• Results First Submitted: 2025-04-17
• Status Verified: 2025-08
• Results First Submitted QC: 2025-08-19
• Last Update Submitted: 2025-08-19
• Results First Posted: 2025-09-09
• Last Update Posted: 2025-09-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 102

Inclusion Criteria

• all providers at Southpoint Rheumatology All patients with a rheumatic disease diagnosis currently prescribed at least one rheumatic medication will be included in the analysis

Exclusion Criteria

• new patients, those who are not prescribed any rheumatic disease medications, or do not have available pharmacy refill data

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Intervention Feasibility as Measured by Number of Providers Agreeing to Participate	4 weeks
Intervention Feasibility as Measured by the Feasibility of Intervention Measure (FIM)	4 weeks	Provider survey based on the Feasibility of Intervention Measure, scores range from 1-5, where 5 is most feasible.
Intervention Feasibility as Measured by Percent of Visits With EMR Documentation of Providers Reviewing Refills	4 weeks	Calculated for the full population, not per participant.

Secondary Outcome Measures

Name	Time	Method
Intervention Acceptability as Measured by the Percentage of Patients Who Report a Positive Feeling After Having an Adherence Conversation With Their Providers	4 weeks	Patient survey will be administered following provider visit.
Fidelity as Measured by the Number of Participants With EMR Documentation of Completing the Intervention Components of Reviewing Pharmacy Refills and Using Effective Communication Strategies	4 weeks
Intervention Acceptability as Measured by the Acceptability of Intervention Measure (AIM)	4 weeks	Provider survey based on the Acceptability of Intervention Measure, scores range from 1-5, where 5 is most acceptable.
Fidelity as Measured by the Number of Participants With Clinicians Conducting the Intervention Components of Reviewing Pharmacy Refills and Using Effective Communication Strategies	4 weeks	This was collected using a EMR Smartphrase where clinicians documented whether they reviewed pharmacy refill data or discussed adherence with patients.
Change in MPR (Medication Possession Ratio) as a Percentage for the Entire Sample	Baseline to 3 months	MPR is calculated by dividing the number of days all patients were covered by medication by the total number of days in the observation period. This is multiplied by 100 to present a percent change for the entire sample.

Trial Locations

Locations (1)

Duke University; 🇺🇸 Durham, North Carolina, United States