To assess relation between hypotension and post operative delirium after anaesthesia in hip surgery

Not yet recruiting

Conditions: Osteoarthritis of hip, unspecified,

Registration Number: CTRI/2022/02/040200

Lead Sponsor: Himalayan Institute of Medical Sciences

Brief Summary: Hip fracture are the commonest reason for elderly people to require emergency surgery ,hospital admission and account for increased orthopaedic trauma bed days than all other fractures.Hip fracture surgery presents various challenges to anesthetists and perioperative physicians.

As a result of advanced age,fraility and comorbidities of many people with hip fracture proceeding with anesthesia and surgery appears high risk.Hypotension occurs during hip fracture surgery .especially in case of older patients with comorbidities.

Elderly hip fracture patients are associated with significantly increased risk of cognitive dysfunction and post operative delirium.Delirium is a common problem in elderly patients and is associated with adverse outcomes,including longer length of hospital stay,decline in function and cognition .

Studies show that temporary brain perfusion of patients become impaired when patients experience prolong low blood pressure,can lead to cognitive impairment.Elderly hip fracture patients are associated with significantly increased risk of cognitive dysfunction and post operative delirium.

Delirium has a fluctuating course and is usually reversible.Development of cognitive dysfunction can be a key issue for increased morbidity and delayed functional recovery in early and late postoperative period.

The study is observational cohort study in which 70 patients are taken as sample size on the basis of previous studies.100% enumeration of cases will be done for duration of 12 months.

The goal of this study is to correlate hypotension in the intraoperative period in regional anesthesia in elderly patients undergoing hip fracture surgery and to assess post operative cognitive dysfunction and delirium in these patients.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 70

Inclusion Criteria

1 ASA physical status I,II and III of either sex 2 Age more than 65 years.
3 Scheduled for hip surgery.

Exclusion Criteria

1.Patient less than 65 years of age.
2.Patient with ASA physical status IV.
2.patient with any spinal deformity 3.Patient with any Cognitive impairment 4.History of hypotension 5.Chronic use of Antipsychotic medications 6.BMI more than 30kg/m2 7.Failed Spinal anaesthesia 8.Patient refusal for regional anaesthesia 9.Any contraindications for Regional anaesthesia.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To study effect of intraoperative hypotension on post operative delirium in elderly hip fracture patients.	To study about delirium in elderly patients 24 hours post hip surgery done under regional anaesthesia with help of delirium scales

Secondary Outcome Measures

Name	Time	Method
To determine effect of any other factors on post operative cognitive outcomes.	To determine association between preoperative comorbidities,functional status and nutritional status as risk factor of 24 hours post operative cognitive dysfunction

Trial Locations

Locations (1): Himalayan institute of Medical sciences
🇮🇳
Dehradun, UTTARANCHAL, India
Himalayan institute of Medical sciences
🇮🇳Dehradun, UTTARANCHAL, India
DrParul Jindal
Principal investigator
9456547229
parulpjindal@yahoo.co.in