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Anti-inflammatory effect of telmisartan in patients with hypertensio

Not Applicable
Conditions
Hypertension
Registration Number
JPRN-UMIN000009186
Lead Sponsor
Division of Nephrology, Department of Internal Medicine, Juntendo University Faculty of Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
60
Inclusion Criteria

Not provided

Exclusion Criteria

(1)Allergy against telmisartan (2)Secondary hyperuricemia (3)Systolic BP > 180mmHg, or diastolic BP > 110mmHg (4)Patients with ALT or AST more than twice (5)History of cardiovascular disease and stroke in the previous 6 months. (6)Pregnant women (7)Patients who are not recommended for participation in this study by physician in charge with medical reasons

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The levels of blood pressure, blood/urinary sTNFRs, TNFalpha, OPG, Osteopontin, hs-CRP, IL-6 and MCP-1
Secondary Outcome Measures
NameTimeMethod
The levels of BW, BMI, e-GFR, albuminuria, serum lipid(TC/TG/HDL-C), and HbA1c
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