Can the experience of a diminished effect of local anesthetics be verified by an objective test?

Phase 1

• Conditions: ocal anesthetics for minor or more major procedures such as suturing lacerations, removing skin lesions, operating ingrown toenails, drilling and removing teeth etc.; MedDRA version: 20.0Level: LLTClassification code 10024760Term: Local anestheticSystem Organ Class: 100000004865; Therapeutic area: Not possible to specify

• Registration Number: EUCTR2019-001450-26-SE
• Lead Sponsor: Institute for Public Health and Caring Sciences, Uppsala University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-05-16
• Last Update Posted: 25 November 2019

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

•Age 18-65
•Patient report of a decreased effect of local anesthetics,
•Signed informed consent

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 20
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

•Previous adverse reaction to local anesthetics (not including decreased effect)
•Injury, infection or peripheral nerve injury in the experimental sites
•Diabetes or medical conditions not suitable for participation in the study
•Use of anticoagulants
•Difficulty to understand written and spoken Swedish.

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified