COMPARATIVE EVALUATION OF TREATMENT OUTCOMES FOR CLASS II FURCATION DEFECTS BY OPEN FLAP DEBRIDEMENT (OFD) ALONE AND OPEN FLAP DEBRIDEMENT (OFD) WITH AUTOLOGOUS PLATELET RICH FIBRIN (PRF) MEMBRANE
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Probing depth, Clinical attachment level
研究概览
简要总结
The periodontal infection results from the subgingival colonization of periodontopathic bacteria. However, subgingival infection can cause anatomic changes in periodontal tissues ( i.e. Increased probing depth [PD], and furcation defects) that can produce local conditions that favor recurrence of disease. Periodontal treatment includes the surgical elimination of anatomic deformities by restoring lost supporting tissues. Periodontal regeneration refers to the reproduction or reconstitution of the lost or injured part. Guided tissue regeneration (GTR) is one technique with the most histologic documentation of periodontal regeneration in class II furcation defect. Various growth factors have been shown to accelerate the healing process. Platelet also releases growth factors which are natural biological mediators that regulate crucial cellular events involved in tissue repair. So platelet rich fibrin will provide growth factors and additionally the simplicity of procedure will help in treatment of class II furcation defect. The aim of this study is to evaluate the effectiveness of autologous platelet rich fibrin (PRF) membrane with open flap debridement (OFD) in the treatment of class II furcation defects compared to open flap debridement (OFD) alone
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 25.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients with age group 25-55 years 2.Both males and females 3.The presence of buccal class II furcation defects in endodontically vital, asymptomatic teeth with a radiolucency in the furcation area on an intraoral periapical radiograph with probing depth (PD)≥ 5 mm and horizontal PD ≥3 mm after phase I therapy (scaling and root planing).
- •4.Absence of any local anatomical limitations 5.Patient willing for surgery and ready to give written consent.
排除标准
- •1.Systemic illness known to affect the outcomes of periodontal therapy 2.Individuals allergic to medications 3.Pregnant or lactating women 4.Patients using tobacco in any form 5.Individuals with unacceptable oral hygiene (plaque index [PI] >1.5).
- •6.Teeth with interproximal intrabony defects, gingival recession, endodontic (pulpal) involvement, or mobility of tooth ≥Grade II will be excluded.
结局指标
主要结局
Probing depth, Clinical attachment level
时间窗: 6 months
次要结局
- Radiographic evaluation(6 months)