COMPARATIVE EVALUATION OF TREATMENT OUTCOMES FOR CLASS II FURCATION DEFECTS BY OPEN FLAP DEBRIDEMENT (OFD) ALONE AND OPEN FLAP DEBRIDEMENT (OFD) WITH AUTOLOGOUS PLATELET RICH FIBRIN (PRF) MEMBRANE
Trial Snapshot
- Phase
- Not Applicable
- Status
- Active, not recruiting
- Sponsor
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Probing depth, Clinical attachment level
Study Overview
Brief Summary
The periodontal infection results from the subgingival colonization of periodontopathic bacteria. However, subgingival infection can cause anatomic changes in periodontal tissues ( i.e. Increased probing depth [PD], and furcation defects) that can produce local conditions that favor recurrence of disease. Periodontal treatment includes the surgical elimination of anatomic deformities by restoring lost supporting tissues. Periodontal regeneration refers to the reproduction or reconstitution of the lost or injured part. Guided tissue regeneration (GTR) is one technique with the most histologic documentation of periodontal regeneration in class II furcation defect. Various growth factors have been shown to accelerate the healing process. Platelet also releases growth factors which are natural biological mediators that regulate crucial cellular events involved in tissue repair. So platelet rich fibrin will provide growth factors and additionally the simplicity of procedure will help in treatment of class II furcation defect. The aim of this study is to evaluate the effectiveness of autologous platelet rich fibrin (PRF) membrane with open flap debridement (OFD) in the treatment of class II furcation defects compared to open flap debridement (OFD) alone
Study Design
- Study Type
- Interventional
- Allocation
- Coin toss, Lottery, toss of dice, shuffling cards etc
- Masking
- Participant Blinded
Eligibility Criteria
- Ages
- 25.00 Year(s) to 55.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •1.Patients with age group 25-55 years 2.Both males and females 3.The presence of buccal class II furcation defects in endodontically vital, asymptomatic teeth with a radiolucency in the furcation area on an intraoral periapical radiograph with probing depth (PD)≥ 5 mm and horizontal PD ≥3 mm after phase I therapy (scaling and root planing).
- •4.Absence of any local anatomical limitations 5.Patient willing for surgery and ready to give written consent.
Exclusion Criteria
- •1.Systemic illness known to affect the outcomes of periodontal therapy 2.Individuals allergic to medications 3.Pregnant or lactating women 4.Patients using tobacco in any form 5.Individuals with unacceptable oral hygiene (plaque index [PI] >1.5).
- •6.Teeth with interproximal intrabony defects, gingival recession, endodontic (pulpal) involvement, or mobility of tooth ≥Grade II will be excluded.
Outcomes
Primary Outcomes
Probing depth, Clinical attachment level
Time Frame: 6 months
Secondary Outcomes
- Radiographic evaluation(6 months)