High fetal catecholamines - a cause for neonatal hypoglycemia and transient hyperinsulinism?
- Conditions
- E16.1P70.4Other hypoglycaemiaOther neonatal hypoglycaemia
- Registration Number
- DRKS00022471
- Lead Sponsor
- niversitätsklinikum Düsseldorf
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 299
Inclusion Criteria
Pregnant women with their unborn child: participants will be assigned to the risk group if the child is IUGR, SGA (birth weight <10th percentile), LGA (birth weight >10th percentile), premature (35+0-36+6 weeks of gestation), has a mother with diabetes/gestational diabetes, pre-/eclampsia or if the child suffers from birth asphyxia. Children without any of the above-mentioned risk factors will be assigned to the control group.
Exclusion Criteria
Lack of parental consent. Prematurity <35+0 weeks of gestation.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) Do infants with different risk factor for hypoglycemia (SGA, IUGR, LGA, late preterm, asphyxiated or have a mother with diabetes or pre-/eclampsia etc.(data will be obtained from the medical file) have higher levels of catecholamines in AF and/or arterial cord blood compared to a control group without risk factors (at the time of birth)? <br><br>2) Do higher levels of catecholamines/its metabolites (in amniotic fluid and/or arterial cord blood at the time of birth) correlate with lower blood glucose levels and longer duration of hypoglycemia (regular blood glucose measurements will be done according to the SOP of our hospital)?
- Secondary Outcome Measures
Name Time Method