NCT02013024已完成不适用
The Effect of Vitrification Versus Slow Freezing on Day 3: a Randomised Controlled Trial.
Sophie Debrock2 个研究点 分布在 1 个国家目标入组 417 人开始时间: 2011年9月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 417
- 试验地点
- 2
- 主要终点
- Life birth rate per embryo thawed
研究概览
简要总结
Randomized controlled trial (RCT) testing the hypothesis that vitrification is superior to slow freezing.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patients (with female age < 40 years)
- •Patients undergoing a 1st oocyte retrieval for an IVF/Intracytoplasmatic Sperm Injection (ICSI) treatment
- •Patients planned for an embryo transfer on day
- •Patients with supernumerary embryos of sufficient quality for freezing/vitrifying on day
- •Fresh personal (own oocytes)
- •One inclusion in the study per patient.
排除标准
- •Patients undergoing a 2nd or higher ranked oocyte retrieval after a fresh cycle with failed pregnancy.
- •Female age ≥ 40 year
- •Patients with Preimplantation Genetic Diagnosis (PGD)
- •Patients with donor oocytes
- •Patients with positive serology whose embryos may not be frozen.
- •Patients planned for a transfer on day 2 or day
- •Patients receiving assisted hatching in the embryo transfer in the frozen cycles.
- •Patients who have been included in the study before.
结局指标
主要结局
Life birth rate per embryo thawed
时间窗: 3 years
次要结局
- survival rate(3 year)
- live birth rate per embryo transferred(3)
- implantation rate per embryo thawed(3 years)
- abortion rate(3 years)
- implantation rate per embryo transferred(3 years)
研究者
Sophie Debrock
clinical embryologist PhD
KU Leuven
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Atrificial Shrinkage of Blastocyst Before In Vitro FertilizationInfertilityNCT04125017Aljazeera Hospital409
已完成
3 期
To evaluate whether rapid freezing is a better method of preserving sperms compared to conventional slow freeze in male factor infertility.CTRI/2015/01/005391Christian Medical Colege Vellore40
已完成
2 期
A Comparison Between Home-made Vitrification & Thawing Media and a Commercially Available Brand on BlastocystBlastocyst DisintegrationNCT03660904Benha University74
终止
2 期
Oocyte Cryopreservation by Slow Freezing and VitrificationWomen Diagnosed With CancerEgg DonorsSingle WomenFailed Sperm Procurement in IVFNCT01223105Reproductive Medicine Associates of New Jersey2
已完成
不适用
Assessment of the New Automated Vitrification System "GAVI" for Early Cleaved Embryos CryopreservationFertility DisordersNCT03478592University Hospital, Toulouse423