Brain Imaging, Heart Rate Variability and Serum Fatty Acid in Subjects With Irritable Bowel Syndrome
Completed
- Conditions
- Irritable Bowel Syndrome
- Registration Number
- NCT02179905
- Lead Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
- Brief Summary
This study is to analyze the relationship between brain structure, the heart rate variability and the serum fatty acid component of the irritable bowel syndrome patients.
- Detailed Description
Several studies showed that the gray matter and white matter of the brain related to the symptoms of irritable bowel syndrome patients.
The investigators study is to analyse the relationship between thickness of cortex of irritable patients, the sympathetic tone and the serum fatty acid component of the irritable bowel syndrome patients. It is to clarify the mechanism of irritable bowel syndrome, whether the symptoms of irritable bowel syndrome are related to the thickness of cortex or inflammation status of the body.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 69
Inclusion Criteria
- female
- between 20 and 50 years old
- meet Rome III criteria
Exclusion Criteria
- colon and small intestinal disease
- psychiatric disease patients
- patients received major surgery in the past 5 years
- diabetic patients
- patients with metal implant
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The relationship between brain structure, heart rate variability and fatty acid of the irritable bowel syndrome patients. Patients who suffered from IBS for more than 5 years.
- Secondary Outcome Measures
Name Time Method The relationship between thickness of brain cortex and the symptoms of irritable bowel syndrome Patients who suffered from IBS for more than 5 years.
Trial Locations
- Locations (1)
Shin Kong Wu Ho-Su Memorial Hospital
🇨🇳Taipei, Taiwan