Effect of brain stimulation and speech-language therapy in the management of grammatical deficits in persons with post-stroke aphasia.
- Conditions
- Health Condition 1: G938- Other specified disorders of brain
- Registration Number
- CTRI/2021/11/037878
- Lead Sponsor
- Rashmi J
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
a) Diagnosis of left hemisphere cerebrovascular accident (CVA) by a medical practitioner and confirmed by CT/MRI scan
b) Post-stroke onset at least > 6 months
c) Rt handedness prior to stroke
d) Individuals with non-fluent aphasia (NFA) diagnosed by an SLP using Western aphasia battery Kannada version
e) Native speaker of Kannada with any dialectical variations
f) Functionally adequate hearing, vision, and ability to follow instructions will be selected based on informal screening
g) Persons with grammatical case marker deficits and word-level verbal output
a) Severe apraxia or dysarthria
b) Contraindication to use tDCS conditions (e.g., history/complaint of seizures, migraine, or skin allergy, cranium metallic implants)
c) Visual field neglect
d) Use of any medications which will affect the cortical excitability (antidepressants, antiepileptic drugs, etc.)
e) Current enrolment in SLT.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Responses from the 100 pictures (50 each in Experimental probe A and Control probe A)Timepoint: Pre-post intervention <br/ ><br>Follow up after one month of intervention
- Secondary Outcome Measures
Name Time Method a) Changes in the amplitude and latency of the P600 ERP component post treatment <br/ ><br>b) Change in the MLU, accuracy and frequency of usage of case markers in sentence production through analysis of speech samples. The response of the participants will be transcribed by the researcher and analysed for the frequency and accuracy of usage of case markersTimepoint: Pre-post intervention <br/ ><br>Follow up after one month of intervention