Effect of Tourniquet Application on Optic Nerve Sheath Diameter
Completed
- Conditions
- Intracranial Pressure Increase
- Registration Number
- NCT04758091
- Lead Sponsor
- Zonguldak Bulent Ecevit University
- Brief Summary
The aim of the study to investigate the effect of tourniquet application on optic nerve sheath diameter (ONSD) and cerebral oxygenation during lower extremity surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1
Inclusion Criteria
- ASA I-II risk group over the age of 18
- Operation planned under general anesthesia
- Lower extremity surgery with a tourniquet
- Agreeing to volunteer for research with an informed consent form
Exclusion Criteria
- Emergency surgical procedures
- neurological disease, carotid disease
- Previous intracranial or ocular surgery
- Neurological symptoms
- cerebral edema, high IntraCranial Pressure
- Presence of glaucoma
- Body mass index (BMI)> 35
- Uncontrolled hypertension
- Diabetic retinopathy
- anemia
- coronary artery disease
- peripheral artery disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method regional cerebral oxgenation during the surgery measurement rSo2 by Near Infrared spectroscopy
optic nerve diameter during the surgery measuring the change in optic nerve diameter
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link tourniquet use to increased intracranial pressure in surgical settings?
How does tourniquet-induced intracranial pressure elevation compare to other surgical stressors in cerebral oxygenation impact?
Are there specific biomarkers that correlate with optic nerve sheath diameter changes during tourniquet application?
What adverse events are associated with tourniquet-related intracranial pressure increases and how are they managed in clinical practice?
What alternative strategies exist for monitoring cerebral oxygenation during lower extremity surgery besides optic nerve sheath diameter measurement?
Trial Locations
- Locations (1)
Zonguldak Bülent Ecevit University Medicine Faculty
🇹🇷Zonguldak, Kozlu, Turkey
Zonguldak Bülent Ecevit University Medicine Faculty🇹🇷Zonguldak, Kozlu, Turkey