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Clinical research of filling extraction sockets with selective COX2 inhibitor-containing paste in patients with mandibular wisdom tooth extractions.

Phase 1
Recruiting
Conditions
third molar
wisdom tooth extraction
D008964
Registration Number
JPRN-jRCTs051230162
Lead Sponsor
Kakei Yasumasa
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
12
Inclusion Criteria

(1) Patients who were planning to have a lower third molar extraction and who were expected to register on the day of extraction.
(2) Patients scheduled for extraction of wisdom teeth classified as Class I and II in the Pell-Gregory classification (horizontal position)
(3) Patients scheduled for extraction of wisdom teeth classified as Positions A and B in the Pell-Gregory classification (vertical position)
(4) Patients aged 18 years or older at the time of acquisition consent.
(5) Patients for whom documented consent has been obtained regarding their voluntary participation in
this clinical study.

Exclusion Criteria

(1) Patients with concurrent severe or uncontrolled concomitant medical conditions.
(2) Patients with history of hypersensitivity to any component of selective COX2 inhibitor, Tween80, Hydroxypropyl cellulose, PEG400.
(3) Patients with aspirin-induced asthma.
(4) Patients who use analgesic drug at least once a week for any chronic pain.
(5) Patients with dementia, psychiatric symptoms, drug addiction and alcoholism
(6) Pregnant or lactating women.
(7) Patients undergoing radiotherapy at the site of a planned wisdom tooth extraction
(8) Patients with a history of drug administration related to medication-related osteonecrosis of the jaw
(9) Patients that the investigator deems inappropriate.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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