Embryo Kinetics and Stimulation Protocol: Recombinant Follicle Stimulating Hormone (FSH) Versus Human FSH

Not Applicable

Terminated

• Conditions: Embryo Kinetics

• Registration Number: NCT01678651
• Lead Sponsor: IVI Madrid

Brief Summary

Different kinetics markers have been proposed to select embryos with higher implantation rates. The effect of external factors on these markers, such as the stimulation protocol should be analyzed. There are two different types of FSH that are commonly used for in vitro fertilization (IVF) in egg donation cycles, recombinant FSH and human FSH. The effect of each kind of hormone on embryo kinetcis is still unknown. The aim of this study is to observe if there is a difference in embryo kinetics and morphology as well as oocyte morphological parameters between the two types of FSH and therefore to analyze if such markers can be used despite of the stimulation protocols chosen.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-08
• Study First Submitted: 2012-08-31
• Study First Submitted QC: 2012-08-31
• Study First Posted: 2012-09-05
• Primary Completion: 2013-02
• Study Completion: 2013-02
• Status Verified: 2015-03
• Last Update Submitted: 2016-02-23
• Last Update Posted: 2016-02-24

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

•Egg donation cycles with more than 8MII in oocyte retrieval day

Exclusion Criteria

• Male factor
• Uterine malformations
• genetic alterations

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
time of cell cleavage	February 2012	Analysis of cell cleavage

Secondary Outcome Measures

Name	Time	Method
Embryo and oocyte morphology	February 2012	Analysis of all oocytes
Outcome rates (implantation, pregnancy and miscarriage rate)	February 2012	Time requierd to know all the implantation, pregnancy and miscarriage rate

Trial Locations

Locations (1)

Insituto Valenciano de Infertilida; 🇪🇸 Madrid, Spain