Measuring the changes in enzymes in the gingival sulcular fluid during orthodontic tooth movement

Phase 1

• Registration Number: CTRI/2019/09/021173
• Lead Sponsor: Manipal College of Dental Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1) Age group of 13-30 years

2) Minimum of 20 remaining teeth

3) Need for fixed appliance therapy involving tooth extractions

4) Good general and periodontal health (probing depths not exceeding 3 mm in the whole dentition, no radiographic evidence of periodontal bone loss, no more than 10% of sites with bleeding on probing, and no gingival redness or edema)

Exclusion Criteria

1)Patients who would not give informed consent

2)Previous history of habits such as alcohol consumption or tobacco use

3)Ongoing orthodontic or orthopedic therapy

4)Any systemic condition that could affect periodontal status and bone metabolism or that would require premedication for monitoring or treatment procedures (eg, heart conditions, joint replacements, hormonal or bisphosphonate antiresorptive therapies, and chronic therapy with heparin or corticosteroids)

5)Use of antibiotics, corticosteroids, or anti-inflammatory drugs within the last 3 months

6)Professional cleaning or periodontal treatment within the last 6 months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified