Comparative evaluation of treatment of infrabony defects with PRF or combination with biphasic calcium phosphate bone graft
- Conditions
- Health Condition 1: R69- Illness, unspecified
- Registration Number
- CTRI/2019/09/021378
- Lead Sponsor
- Sruthy Madhusudanan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
I. Patients without systemic diseases or conditions that could influence therapy outcome
II. Patients who are not taking any medication that would affect periodontal healing
III. High standards of oral hygiene (Oâ??Leary et al.: plaque control record [PCR] <20%)
IV. compliance with the maintenance program
V. presence of at least one infrabony defect with a PD >= 6 mm after reevaluation of the hygienic phase and an infrabony component of >=3 mm as detected on radiographs and exhibiting a 1- or 2-wall infrabony defect
VI. presence of at least 2 mm of keratinized tissue on the buccal aspect of the selected tooth
VII. Teeth have to be vital or properly treated endodontically
1) Heavy smokers ( >10 cigarettes/day)
2) teeth with Class II or III furcation involvement(Glickman classification)
3) mobility >grade II(Glickman classification)
4) Strictly or predominantly 3-wall defects
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1) To evaluate and compare the clinical and radiographic parameters before and after the use of PRF alone and PRF in combination with biphasic tricalcium phosphate bone graft in the treatment of infrabony defect <br/ ><br>2) To compare the efficacy of PRF alone with PRF and biphasic tricalcium phosphate bone graft combination in treatment of infrabony defects using clinical and radiographic parametersTimepoint: 10mins
- Secondary Outcome Measures
Name Time Method To evaluate and compare the alkaline phosphatase level in gingival crevicular fluid before and after the use of PRF alone and PRF and biphasic tricalcium phosphate bone graft combinationTimepoint: 15mins