Application of hyaluronic acid in the treatment of periodontitis (gum disease)

Not Applicable

Completed

• Conditions: Surgical treatment of intrabony vertical defects in patients with Periodontitis stage III, grades A and B; Oral Health

• Registration Number: ISRCTN22392064
• Lead Sponsor: niversity of Medicine and Farmacy Victor Babes Timisoara

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2023-12-01
• Study Start: 2024-03-12
• Last Update Posted: 25 March 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. No systemic diseases that could in?uence the outcome of the therapy
2. Presence of 2-3 walls IBD = 3 mm
3. An interproximal PD = 6 mm
4. 6 weeks after subgingival instrumentation at the experimental sites
5. Good oral hygiene
6. Non-smokers

Exclusion Criteria

1. Patients with systemic diseases known to affect the outcome of periodontal therapy
2. Immunocompromised individuals
3. Pregnant or lactating females
4. Tobacco smokers or tobacco use in any form
5. Non-compliant patients
6. Prolonged antibiotic treatment or anti-inflammatory treatment within 6 months prior the surgery
7. Grade C periodontitis
8. Furcation involvement at the same tooth
9. Mobility grade II/III
10. Poor oral hygiene
11. Patients with parafunctional habits
12. Patients who had periodontal surgery in the last 6 months
13. Orthodontic treatment during the previous year
14. Occlusion trauma
15. Interproximal open contact points
16. One-walled or combined one- and two-walled defects confirmed upon surgical exposure

Study & Design

• Study Type: Interventional
• Study Design: Not specified