Evaluation the effect of dexmedetomidine administration during surgery on intraoperative hemodynamic factors and postoperative analgesic consumption in opium addicted patients
Phase 2
- Conditions
- Femoral Neck Fracture.Fracture of neck of femur
- Registration Number
- IRCT201608019593N4
- Lead Sponsor
- Vice chancellor for research, Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
age 18-75; Femoral neck fracture; candidate for surgery under spinal anesthesia; history of opium abuse for at least 6 weeks
Exclusion criteria: Pregnancy; breast feeding; history of chronic pain; long term analgesic use; BMI>35; diabetic; ischemic heart disease; cerebral vascular attacks; hypertension; malignancy; renal failure; hepatic failure; coagulopathy; history of drug allergy; need for blood transfusion during surgery; intolerance for spinal anesthesia
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Analgesic consumption. Timepoint: Until 24 hours after surgery. Method of measurement: Calculating the total dose of analgesic consumption by the researcher.
- Secondary Outcome Measures
Name Time Method Pain onset. Timepoint: After finishing the surgery until first request for analgesic. Method of measurement: Time measurment by researcher based on minutes.;Hemorrhage volume. Timepoint: From the begining until the end of surgry. Method of measurement: Calculating the bleeding volume based on mililiter by researcher.;Hemodynamic side effects. Timepoint: From drug administration until end of surgry. Method of measurement: Assessing hemodynamic changes using special monitoring device.