Cleavage Pattern of Embryos and Oxidative Parameters

Not Applicable

• Conditions: Infertility
• Interventions: Diagnostic Test: oxidative stress measurement

• Registration Number: NCT03791931
• Lead Sponsor: Carmel Medical Center

Brief Summary

To investigate prospectively whether embryos with abnormal cleaving pattern have different oxidative parameters from normally cleaving embryos, and to analyze whether these parameters have an association with demographic, laboratory and clinical parameters including treatment outcome.

Detailed Description

To investigate prospectively whether embryos with abnormal cleaving pattern have different oxidative parameters from normally cleaving embryos, and to analyze whether these parameters have an association with demographic, laboratory and clinical parameters including treatment outcome.

Study Timeline

• Study First Submitted: 2018-12-26
• Study First Submitted QC: 2019-01-01
• Study First Posted: 2019-01-03
• Study Start: 2019-07-07
• Status Verified: 2020-02
• Last Update Submitted: 2020-02-02
• Last Update Posted: 2020-02-05
• Primary Completion: 2021-01-01
• Study Completion: 2021-04-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Patients undergoing IVF for the treatment of infertility

Exclusion Criteria

• Age <18 or >45 years old
• Patients with no embryos with direct cleavage

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Patients	oxidative stress measurement	Oxidative stress measurement in cleavage state embryos

Primary Outcome Measures

Name	Time	Method
clinical pregnancy rate	1 year	Clinical pregnancy as defined by appearance of gestational sac on ultrasound
implantation rate	1 year	Implantation rate (positive BHCG)

Trial Locations

Locations (1)

Carmel Medical Center; 🇮🇱 Haifa, Israel