Turmeric in the treatment of recurrent aphthous stomatitis

Phase 2

• Conditions: Recurrent aphthous stomatitis.; Recurrent oral aphthae; K 12.0

• Registration Number: IRCT201107311556N28
• Lead Sponsor: Erphan Teb

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

50 Patients between 20 and 45 years old will be included if they present with 1–5 aphthous ulcers of less than 24 h duration. The ulcers diameter will not be greater than 6 mm and they do not suffer from acute or chronic diseases of the oral mucosa Patients will be excluded from the study if they have concurrent clinical conditions including serious liver, kidney, and heart dysfunctions or if they have ulcers as a manifestation of a systemic disease process such as ulcerative colitis, Crohn’s disease, Behcet’s syndrome, or serious anaemia. To minimize the effect of confounding variables in the psycho- physiological component of the study, the patients should not have a history of alcohol or drug abuse and should not take any narcotic analgesics. Patients will be excluded if they have a history of systemic immunosuppressive therapy.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Decrease of pain. Timepoint: Before treatment and days 2, 4, 6, 10 and 14 after treatment. Method of measurement: VAS rating scale.

Secondary Outcome Measures

Name	Time	Method
Size of ulcers. Timepoint: Before drug application (day 0) and at days 2, 6, 10 and 14. Method of measurement: Diameters.