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临床试验/NCT03009318
NCT03009318已完成不适用

Combination of 11C-MET PET and MRS in the Diagnosis of Glioma.

Huashan Hospital1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2012年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
100
试验地点
1
主要终点
Sensitivity of the combination of MRS and 11C-MET PET/CT

研究概览

简要总结

MET PET and MRS are often performed as imaging tool for the differential diagnosis of gliomas. But both techniques have limitations causing misdiagnosis; thus, the investigators tried to combine these two imaging tools to study whether the combination of MET PET and MRS could raise the diagnosis ability of the radiological diagnosis of gliomas.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients with non-enhancing supratentorial lesions shown by contrast-enhanced MRI
  • No surgery, chemotherapy or radiotherapy history
  • All patients gave written informed consent.

排除标准

  • Patients with infratentorial Neoplasms
  • Patients with enhancing supratentorial lesions
  • Recurrent gliomas after surgery
  • Primary gliomas with history of radiotherapy or chemotherapy
  • History of malignant tumours at any body site
  • Inability to give informed consent

结局指标

主要结局

Sensitivity of the combination of MRS and 11C-MET PET/CT

时间窗: 5 years

次要结局

  • The relationship between 11C-MET PET/CT results and molecular pathogeneses(5 years)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dongxiao Zhuang

Professor

Huashan Hospital

研究点 (1)

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