The Effect of Colchicine in prevention of Pericardial Effusion after CABG
Phase 3
- Conditions
- Condition 1: post cabg pericardial effusion. Condition 2: post cabg pericarditis.
- Registration Number
- IRCT20211221053477N1
- Lead Sponsor
- Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 260
Inclusion Criteria
All patients referred to Fatemeh Zahra Heart Hospital with coronary artery disease who are candidates for coronary artery bypass graft surgery
Exclusion Criteria
Patients over 80 years old
Presence of pericardial effusion in preoperative trans-thoracic echo
Existence of pleural effusion in CXR standing before surgery
Chronic lung, liver disease (known case of liver disease or LFT more than 3 times normal) and kidney disease (known case of kidney disease or Cr> 2.5)
Other heart surgeries at the same time as coronary artery bypass grafting
Patients who was allergic reaction to colchicine or given colchicine in any way are contraindicated
pregnant patients
Patients receiving colchicine before starting of study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pericardial effusion. Timepoint: Before discharg and 14 days after surgery. Method of measurement: echocardiography.
- Secondary Outcome Measures
Name Time Method Pleural effusion. Timepoint: Before discharge and 14 days after surgery. Method of measurement: echocardography.;Pericarditis. Timepoint: Before discharge and 14 days after surgery. Method of measurement: Echocardiography and clinical history.