Efficacy Testing of Hibiscus Sabdariffa Extract and Collagen Products
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- TCI Co., Ltd.
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- The change of skin wrinkles
Study Overview
Brief Summary
To assess Hibiscus sabdariffa extract and collagen products on skin condition improvement
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Other
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 20 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Healthy adults aged above 20 years old
Exclusion Criteria
- •Subject who is not willing to participate in this study.
- •Patients with diseases of the skin, liver, kidney.
- •Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
- •Female who is pregnant or nursing or planning to become pregnant during the course of the study.
- •Received facial laser therapy, chemical peeling or UV overexposure (> 3 hr/week) in the past 4 weeks.
- •Constant drug use
- •Students who are currently taking courses taught by the principal investigator of this trial.
Outcomes
Primary Outcomes
The change of skin wrinkles
Time Frame: Week 0, week 4, week 8
VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units
The change of skin elasticity
Time Frame: Week 0, week 4, week 8
SoftPlus was utilized to measure skin elasticity. Units: arbitrary units
The change of skin moisture
Time Frame: Week 0, week 4, week 8
Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120
The change of skin texture
Time Frame: Week 0, week 4, week 8
VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units
The change of skin collagen density
Time Frame: Week 0, week 4, week 8
DermaLab® Series SkinLab Combo was utilized to measure skin pores. Units: arbitrary units
Secondary Outcomes
- The change of skin L* value(Week 0, week 4, week 8)
- The change of skin spots(Week 0, week 4, week 8)
- The change of skin melanin index(Week 0, week 4, week 8)
- The change of transepidermal water loss (TEWL)(Week 0, week 4, week 8)
- The change of skin pores(Week 0, week 4, week 8)