Predictive factors of persistence of ascites after TIPS implantatio

Recruiting

• Conditions: K74; Fibrosis and cirrhosis of liver

• Registration Number: DRKS00019015
• Lead Sponsor: niversitätsklinikum Freiburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-12-20
• Results First Posted: 2023-07-26
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

Patients with TIPS implantation

Exclusion Criteria

Patients without TIPS implantation

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
a) Analysis of ADH after TIPS implantation and correlation with the persistence of ascites after TIPS implantation<br>b) Analysis of predictive factors for persistence of ascites after TIPS implantation<br>c) Influence of the oncotic and hydrostatic pressure on the persistence of ascites after TIPS implantation<br>d) Analysis of the baseline activation status of platelets before TIPS implantation<br>e) Influence of the stent graft on platelet function<br>f) Influence of antithrombin and clotting factor VIII on the development of TIPS thrombosis

Secondary Outcome Measures

Name	Time	Method
a) Correlation of ADH with degree of liver dysfunction (clinical and laboratory parameter and scores)<br>b) Correlation of ADH with the oncotic and hydrostatic pressure and indication for TIPS implantation (ascites vs. varices)<br>c) Correlation of platelet function, antithrombin and clotting factor VIII with liver function<br>d) c) Correlation of platelet function, antithrombin and clotting factor VIII with indication for TIPS implantation (ascites vs. varices)