COgnitive bias modification to Prevent dEpression (COPE trial)

Not Applicable

• Conditions: Depressive disorder; Subsyndromal depression; Mental Health - Depression

• Registration Number: ACTRN12613001334796
• Lead Sponsor: niversity of Western Australia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-12-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 510

Inclusion Criteria

Patient Health Questionnaire (PHQ-9) total score between 5 and 14 (inclusive)
- Age 45 years or over
- Fluent in written and spoken English
- Easy daily access to a computer with internet connection

Exclusion Criteria

- Current major depressive episode according to DSM-V criteria
- Past diagnosis of schizophrenia, schizoaffective disorder or bipolar disorder
- Past clinical history of stroke or of neurodegenerative diseases (e.g., Parkinson's disease)
- Evidence of harmful or hazardous consumption of alcohol (Alcohol Unit Disorders Identification Test - AUDIT = 15)
- Evidence of cognitive impairment (Modified Telephone Interview for Cognitive Status, TICSm < 27)
- Severe visual impairment that compromises ability to read
- Severe medical illness that may compromise ongoing participation in the study for 12 months (e.g., metastatic cancer)
- No general practitioner
- No written informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Major depressive episode according to DSM-V criteria.[Weeks 11, 27 and 52.];Clinically significant symptoms of depression, established by a score of 15 or greater on the Patient Health Questionnaire (PHQ-9).[Weeks 6, 11, 15, 19, 23, 27, 36, 44, 52.]