COMPARISON OF EFFECT OF DRUGS TO PREVENT FALL IN BLOOD PRESSURE ON FETAL ACIDOSIS INWOMEN UNDERGOING ELECTIVE CAESAREAN DELIVERYUNDER SPINAL ANAESTHESIA
Not Applicable
Completed
- Conditions
- Health Condition 1: O80- Encounter for full-term uncomplicated deliveryHealth Condition 2: O80- Encounter for full-term uncomplicated delivery
- Registration Number
- CTRI/2020/03/023986
- Lead Sponsor
- Apoorva Singh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Full term, non-labouring pregnant females
ASA physical status II
Scheduled for elective CD under spinal anaesthesia
Exclusion Criteria
Refusal of the patient to participate in the study.
Any known co-morbidities, such as hypertensive disorders of pregnancy, diabetes,
cardiovascular diseases, cerebrovascular diseases, established presence of arrhythmias.
Any known fetal abnormality or fetal distress, multiple gestation, ruptured membranes with
meconium stained liquor, growth restricted foetus having chronic asphyxia (previous
abnormal non-stress test and biophysical profile <6), evidence of intrauterine infection.
Recent use of any vasoactive medication.
Any contraindication to spinal anaesthesia.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cord blood base deficit in noradrenaline group as compared to phenylephrine groupTimepoint: At the time of delivery
- Secondary Outcome Measures
Name Time Method APGAR scores of the neonateTimepoint: 1 minute, 5 minutes and 10 minutes;Final outcome of the neonate and neonatal mortalityTimepoint: At the time of discharge from hospital;Intraoperative nausea, vomiting, headacheTimepoint: Intraoperatively;Maternal hemodynamicsTimepoint: Intraoperatively;Requirement of neonatal resuscitationTimepoint: After birth;Umbilical artery blood PaCO2Timepoint: At the time of delivery;Umbilical artery blood PaO2Timepoint: At the time of delivery;Umbilical artery blood pHTimepoint: At the time of delivery