Identify the Genes Polymorphisms Related to Non-familial Bradyarrhythmia

• Conditions: Bradyarrhythmia

• Registration Number: NCT01310907
• Lead Sponsor: China Medical University Hospital

Brief Summary

Bradyarrhythmia, including sinus node dysfunction and atrioventricular block, is a major cause necessitating pacemaker implantation. In contrast to familial bradyarrhythmia known as by mutations at particular ion channels, limited information is available for the mechanistic study in non-familial bradyarrhythmia.

Possible gene polymorphisms related to non-familial bradyarrhythmia were studied. Comparison of multi-locus analysis and single-locus analysis will be analyzed between the cases and controls. Functional studies will perform to clarify the results of association study.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-02
• Status Verified: 2011-03
• Study First Submitted: 2011-03-06
• Study First Submitted QC: 2011-03-06
• Last Update Submitted: 2011-03-06
• Study First Posted: 2011-03-09
• Last Update Posted: 2011-03-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• The patients with non-familial bradyarrhythmia

Exclusion Criteria

• Familial bradyarrhythmia Reversible bradyarrhythmia Bradyarrhythmia after open heart surgery and severe organic heart diseases

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

China Medical University Hospital; 🇨🇳 Taichung, Taiwan