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Consciousness-based Ayurveda Lifestyle Program for Improving Quality of Life in Survivors of Breast Cancer

Not Applicable
Active, not recruiting
Conditions
Breast Cancer Survivors
Interventions
Behavioral: Ayurvedic lifestyle protocol
Registration Number
NCT05743023
Lead Sponsor
Robert Schneider, MD
Brief Summary

This study is a pilot study to assess the feasibility and effectiveness of a 12-week intervention of personalized diet and lifestyle protocol based on the principles of Ayurveda's whole systems approach to achieving improvement in a) quality of life, b) digestive health, c) sleep among women breast cancer survivors.

Detailed Description

Breast cancer is the most common cancer among women worldwide. Due to advancements in early diagnosis and treatment, the survival rate of breast cancer has significantly increased. According to the National Cancer Institute's office of cancer survivorship, as of January 2019, there are 3.8 million breast cancer survivors.

Evidence indicates that cancer survivors experience many adverse effects of treatment and suffer from significant quality of life (QOL) challenges such as depression, anxiety, emotional, social, psychological, physiological, and spiritual wellbeing.

Personalized diet, lifestyle and daily routine approaches to breast cancer survivorship are often undervalued. Generally, the dietary guidelines are based only on an individual's nutritional and caloric needs.

Due to the increasing number of breast cancer survivors, it has become essential to have evidence-based guidelines for breast cancer survivorship to improve digestive health, QOL, and general wellbeing. Understanding the science behind personalized lifestyle-related factors, including diet, exercise, and emotional and spiritual wellbeing in cancer survivorship, is urgently needed. Digestive health and the gut microbiome may play an important role in the QOL after surviving breast cancer; however, there are fewer studies on the relationship between diet and daily routine to gut health and breast cancer survivorship care.

This study will test whether personalized guidelines based on the principles of Maharishi Ayurveda - a whole systems approach to reducing strength, improving digestive health and living in harmony with the circadian rhythm to improve QOL for women diagnosed and treated for breast cancer. In addition to that, this pilot study may provide preliminary data to further develop a clinical practice guideline that is cost-effective and easy to follow for women breast cancer survivors.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
Female
Target Recruitment
15
Inclusion Criteria
  • A breast cancer survivor in remission (Females ≥ 18 years)
  • Diagnosis of stage I-IV breast cancer
  • Three months or more after receiving conventional treatment (chemotherapy, radiation therapy, and/or surgery)
  • Willing to comply with the study intervention recommendations for 12 weeks
  • English speaking
  • Have access to technology to participate in zoom visits
Exclusion Criteria
  • Male responders
  • Inability to provide informed consent
  • Physiological or psychological debility that would interfere with the ability to participate in the study fully
  • Active metastatic or recurrent disease (to avoid early withdrawal from the study)
  • Anticipates undergoing surgery during the duration of the intervention
  • Substance abuse (to avoid early withdrawal from the study)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Waitlist controlAyurvedic lifestyle protocolParticipants in the waitlist control group will not receive any intervention. They will continue usual care and will be asked to complete the self-reported questionnaires at baseline, 6, and 12-week. Participants n this group receive their personalized protocol at the end of 12 weeks after completing all the data collection.
Consciousness-based Ayurvedic lifestyle InterventionAyurvedic lifestyle protocolIn the intervention group, each participant will receive a structured education and be asked to follow a 12-week personalized diet and daily routine protocol based on the assessment of their current Ayurvedic mind-body state. Participants will be asked to complete the self-reported questionnaires at baseline, 6, and 12-week.
Primary Outcome Measures
NameTimeMethod
Change in Sleep disturbance0, 6 weeks and 12 weeks

Assess change from baseline sleep disturbance to 6 and 12 weeks.

Researchers will use the following Self-reported outcome measure instruments:

Assessment using the General Sleep Disturbance Scale (GSDS).

Change in Quality of life0, 6 weeks, and 12 weeks

Assess change from baseline quality of life to 6 and 12 weeks.

Researchers will use the following Self-reported outcome measure instruments:

Quality of life: Quality of Life instrument (cancer patient/cancer survivor version) developed by the City of Hope National Medical Center in California.

Change in Digestive health0, 6 weeks, and 12 weeks

Assess change from baseline digestive health to 6 and 12 weeks.

Researchers will use the following Self-reported outcome measure instruments:

Ayurvedic assessment of digestive strength questionnaire and Gastrointestinal Symptoms Rating Scale (GSRS) for the gut health assessment.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Maharishi International University

🇺🇸

Richmond, California, United States

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