Clinical and Genetic Factors on the Postoperative Recovery Time of General Anaesthesia

Completed

• Conditions: General Anesthesia

• Registration Number: NCT02822417
• Lead Sponsor: Yijing He

Brief Summary

To evaluate the effect of clinical factors on the recovery time of postoperative anesthesia and the effect of genetic variation in gDNA on the recovery time of postoperative anesthesia.

Detailed Description

Recovery time of postoperative anesthesia is an important index to reflect patient's postoperative health status. The investigators want to collect patients' clinical dates and their blood samples, then extract DNA from blood samples, acquire every patients' genetic variation information. Finally, acquiring the mathematical model of the influence of clinical factors and genetic factors on the recovery time after operation, predicting the recovery time of anesthesia.

Study Timeline

• Study Start: 2016-06-01
• Study First Submitted: 2016-06-30
• Study First Submitted QC: 2016-07-01
• Study First Posted: 2016-07-04
• Primary Completion: 2017-10-10
• Study Completion: 2017-12-31
• Status Verified: 2018-07
• Last Update Submitted: 2018-07-09
• Last Update Posted: 2018-07-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1453

Inclusion Criteria

1. Aged more than 18 years;
2. General anesthesia for all patients;
3. Patients underwent surgery for laparoscopic surgery, orthopedics surgery or open surgery;
4. Patients were not delivered allogeneic blood in three months;
5. Having the ability to understand and sign the informed consent.

Exclusion Criteria

1. Pregnant or lactating women;
2. Having an immune deficiency, as a patient with HIV infection;
3. Patients with infectious diseases, such as syphilis;
4. Patients delivered allogeneic blood in three months;
5. Researchers believe that may increasing the risk of subjects or interfering clinical trial;
6. Don't have the ability to understand or sign the informed consent.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Recover time of anesthesia	within 24 hours

Trial Locations

Locations (1)

Xiangya Hospital Central South University; 🇨🇳 Changsha, Hunan, China