Clinical and Genetic Factors on the Postoperative Recovery Time of General Anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,453
- 试验地点
- 1
- 主要终点
- Recover time of anesthesia
研究概览
简要总结
To evaluate the effect of clinical factors on the recovery time of postoperative anesthesia and the effect of genetic variation in gDNA on the recovery time of postoperative anesthesia.
详细描述
Recovery time of postoperative anesthesia is an important index to reflect patient's postoperative health status. The investigators want to collect patients' clinical dates and their blood samples, then extract DNA from blood samples, acquire every patients' genetic variation information. Finally, acquiring the mathematical model of the influence of clinical factors and genetic factors on the recovery time after operation, predicting the recovery time of anesthesia.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged more than 18 years;
- •General anesthesia for all patients;
- •Patients underwent surgery for laparoscopic surgery, orthopedics surgery or open surgery;
- •Patients were not delivered allogeneic blood in three months;
- •Having the ability to understand and sign the informed consent.
排除标准
- •Pregnant or lactating women;
- •Having an immune deficiency, as a patient with HIV infection;
- •Patients with infectious diseases, such as syphilis;
- •Patients delivered allogeneic blood in three months;
- •Researchers believe that may increasing the risk of subjects or interfering clinical trial;
- •Don't have the ability to understand or sign the informed consent.
结局指标
主要结局
Recover time of anesthesia
时间窗: within 24 hours
次要结局
未报告次要终点
研究者
Yijing He
Associate professor
Central South University