comparison of low dose clonidine and dexmedetomidine as a supportive agentto levobupivacaine in spinal anaesthesia

Phase 2

Not yet recruiting

• Conditions: Health Condition 1: O- Medical and Surgical

• Registration Number: CTRI/2023/11/060123
• Lead Sponsor: Department of Anaesthesiology School of Medical Sciences and Research Sharda University.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 19 December 2023

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1.Patient scheduled for surgery under subarachnoid block

2.Age 18-60 years

3.Both genders

4.ASA grade I and II

Exclusion Criteria

1.Morbid obesity BMI >30kg permeter square

2.Patient with history of adverse response to study drugs

3.Patient with pre-existing neurological or spinal disease cardiovascular disease renal hepatic or any other systemic disease

4.Pregnant females

5.Coagulopathy or bleeding diathesis

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the effect of low dose intrathecal clonidine versus dexmedetomidine as anadjuvant to 0.5 percentage hyperbaric levobupivacaine in subarachnoid block in respect to <br/ ><br>1.To compare the time of onset & duration of sensory blockade assessed by pinprick & Visual Analog Score VAS respectively. <br/ ><br>2.To compare the time of onset & duration of motor blockade assessed by modified Bromage scale <br/ ><br>Timepoint: Post operative period

Secondary Outcome Measures

Name	Time	Method
Changes in vitals parameters heart rate noninvasive blood pressure & oxygen saturation SPo2 <br/ ><br> <br/ ><br>2.Requirementoffirst analgesicrescueinpostoperativeperiodin thefirst 24hours. <br/ ><br>Timepoint: Post operative perriod