Comparision of two different doses of buprenorphine as add on to levobupivacaine in arthroscopic lower limb surgeries:A randomized double-blind study
Phase 4
Not yet recruiting
- Conditions
- Health Condition 1: M968- Other intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified
- Registration Number
- CTRI/2024/04/066084
- Lead Sponsor
- Dr Vivek Sharma
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA Class I/II undergoing arthroscopic lower limb surgeries under subarachnoid block
Exclusion Criteria
oH/o hypersensitivity reaction to local anaesthetics
oUncontrolled hypertension, diabetes mellitus and morbid obesity
oContraindication to spinal anaesthesia.
oHistory of alcohol or drug abuse and patients on Chronic opioid
oPatient not giving consent
oPatients undergoing emergency surgery
oPregnant and lactating females
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare duration of analgesia- Time from intrathecal injection till administration of first rescue analgesic for 24 hoursTimepoint: To compare duration of analgesia- Time from intrathecal injection till administration of first rescue analgesic for 24 hours
- Secondary Outcome Measures
Name Time Method 1-To compare the time taken for onset of sensory block <br/ ><br>Time taken from the end of injection to loss of pin prick sensation at T10 dermatome <br/ ><br>2-To compare the time taken for onset of motor block -The time taken to achieve a score of 2 on the modified Bromage scale. [9] <br/ ><br>3-To compare the duration of sensory block- It will be two-segment regression time from highest level of sensory blockade. <br/ ><br>4-To compare the duration of motor block- The duration of the motor block will be defined as the time interval between the onset of motor block (modified Bromage scale 2) to the achievement of modified Bromage scale 6 after the surgery. <br/ ><br>Safety outcome- Recording and reporting of adverse events(nausea,vomiting,respiratory depression) will be collected <br/ ><br>Timepoint: intraoperative and postoperative