COMPARISON OF EFFECTS OF GENERAL ANAESTHESIA INDUCTION WITH THIOPENTONE-FENTANYL AND PROPOFOL-FENTANYL COMBINATIONS ON LEFT VENTRICULAR FUNCTION ASSESSED BY TRANSTHORACIC ECHOCARDIOGRAPHY: A ONE YEAR RANDOMISED CLINICAL TRIAL
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- TO ASSESS THE EFFECTS OF THIOPENTONE-FENTANYL VS. PROPOFOL-FENTANYL ON LEFT VENTRICULAR SYSTOLIC FUNCTION IN PATIENTS UNDERGOING NON-CARDIAC SURGERIES UNDER GENERAL ANAESTHESIA USING TRANS-THORACIC ECHOCARDIOGRAPHY
研究概览
简要总结
Post induction hypotension is a known complication in patients undergoing general anaesthesia. It has been observed with both Thiopentone-Fentanyl and Propofol-Fentanyl as induction agents.
Hypotension in these scenarios may be due to decreased systemic vascular resistance or decreased systolic function of the heart.
While both Thiopentone and Propofol have ben studied extensively as standalone agents, their respective combinations with Fentanyl have not been studied thoroughly in patients undergoing non-cardiac surgeries under GA
We aim to study the effects of aforementioned combinations as induction agents for general anaesthesia on systolic function of the heart in a non-invasive manner with the help of trans-thoracic echocardiography in the operating room
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •American Society of Anaesthesiologists physical status I and II.
- •Age between 18 to 60 years.
- •Patients undergoing elective surgeries under general anaesthesia.
- •Provides Consent.
排除标准
- •Patient undergoing emergency surgery.
- •Patient who are unable or unwilling to give consent.
- •Patients who do not fulfil inclusion criteria.
- •Pre-existing cardiac diseases (Ischaemic Heart Disease, valvular and congenital heart diseases) Pregnant Females.
结局指标
主要结局
TO ASSESS THE EFFECTS OF THIOPENTONE-FENTANYL VS. PROPOFOL-FENTANYL ON LEFT VENTRICULAR SYSTOLIC FUNCTION IN PATIENTS UNDERGOING NON-CARDIAC SURGERIES UNDER GENERAL ANAESTHESIA USING TRANS-THORACIC ECHOCARDIOGRAPHY
时间窗: Pre-Operative | 3 minutes post induction of anaesthesia
次要结局
- There is No Secondary Objective(There is No Secondary Objective)