Effects of Two Sugar Substituted Chewing Gums Plus Tooth Brushing on Different Caries and Gingivitis Related Variables: a Double Blind, Randomized Controlled Clinical Trial
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 130
- 试验地点
- 1
- 主要终点
- Turesky index
研究概览
简要总结
The purpose of this study is to determine the effect of three times a day mastication, during a follow-up period of 4 weeks, of two sugar-substituted chewing gums on various factors associated with dental caries and gingivitis.
详细描述
The purpose of this paper is to compare the effect of daily consumption of two sugar-free chewing gum, one with Recaldent and one with Xylitol, added to traditional hygiene (brushing, fluoridated toothpaste and dental floss), in clinical features such as the accumulation of plaque and gingival inflammation, microbiological characteristics of saliva as the counts of cariogenic microorganisms and facultative anaerobes, and some physicochemical properties of saliva such as pH and concentrations of calcium and inorganic phosphate.
To this there was a general call among dental students at the University of Antioquia and those who expressed their intention to participate voluntarily with informed consent, were examined clinically and randomly assigned to one of the study groups (Recaldent or Xylitol) or the control group.
After a month of baseline examination and the daily use of the same instruments of oral hygiene and chewing of 6 pellets of each chewing gum (in the case of study groups), all variables are re-examined.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 16 Years 至 34 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •systemically healthy
- •dental student
排除标准
- •less than 26 teeth in mouth
- •use of orthodontic appliances
- •use of antibiotics the last 3 months
结局指标
主要结局
Turesky index
时间窗: a month
dental plaque assessment
次要结局
- Gingival index(a month)
- salivary pH(a month)
- Streptococcus mutans(a month)
- Ca levels(a month)
- facultative microorganisms(a month)
- Lactobacillus(a month)
- phosphate levels(a month)
- BOP index(a month)
研究者
María Cecilia Martínez-Pabón
Profesora Asociada
Universidad de Antioquia