Expiratory Flow Limitation and Postoperative Complications

Completed

• Conditions: Postoperative Respiratory Complications

• Registration Number: NCT02229591
• Lead Sponsor: Università degli Studi di Ferrara

Brief Summary

Expiratory flow limitation (EFL) occurs when flow ceases to increase with increasing expiratory effort. In any circumstances EFL predisposes to pulmonary dynamic hyperinflation and its unfavorable effects such as increased elastic work of breathing, inspiratory muscles dysfunction, and progressive neuroventilatory dissociation, leading to reduced exercise tolerance, marked breathlessness during effort, and severe chronic dyspnea. Our hypothesis is that EFL should affect post operative outcomes like incidence of pulmonary complication and length of stay in hospital

Detailed Description

Not available

Study Timeline

• Study Start: 2013-01
• Study First Submitted: 2014-08-28
• Study First Submitted QC: 2014-08-28
• Study First Posted: 2014-09-01
• Primary Completion: 2016-08
• Study Completion: 2016-09
• Status Verified: 2016-10
• Last Update Submitted: 2016-10-25
• Last Update Posted: 2016-10-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 330

Inclusion Criteria

• General anesthesia
• Duration of the surgery >2 hours

Exclusion Criteria

• <18 years
• Consensus not given

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pulmonary complication	28 days	Postoperative pulmonary complication such infection, acute respiratory distress, post operative desaturation

Trial Locations

Locations (1)

Azienda Ospedaliero Universitaria Sant'Anna; 🇮🇹 Ferrara, Italy