Does Adding Magnesium Sulphate to Low Dose Rocuronium Affects the Depth of Blockade in Cancer Patients Undergoing Direct Laryngoscope Surgical Procedures
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Onset and duration of muscle relaxant
研究概览
简要总结
This study aim is to compare the effect of magnesium sulphate combined with low dose rocuronium versus standard dose rocuronium
详细描述
Comparing the effect of magnesium sulphate combined to low dose rocuronium versus standard dose rocuronium in cancer patients undergoing direct laryngoscopy for laryngeal tumors regarding intubating conditions, intraoperative relaxation, depth of anesthesia and recovery time.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with Laryngeal tumors
- •Age 30-70 years
排除标准
- •Renal and or hepatic insufficiency
- •Neuromuscular disease
- •Large glottic and/or supra-glottic lesions with or without breathing difficulties
- •Known allergy to any of the used drug
研究组 & 干预措施
Standard rocuronium
patients received rocuronium 0.6mg/kg
干预措施: standard rocuronium dose (Drug)
Magnesium
patients received 100 ml saline with 50mg/kg magnesium sulphate infusion over 10 minutes
干预措施: Magnesium sulfate (Drug)
结局指标
主要结局
Onset and duration of muscle relaxant
时间窗: 90 minutes
Onset time of muscle relaxant and duration
次要结局
- Degree of muscle relaxation(90 minutes)
研究者
Walaa Youssef Elsabeeny
Lecturer of anesthesia and pain management
National Cancer Institute, Egypt