A new approach to determine the time of incidence of traumatic brain injury with chronic subdural hematomas.

Completed

• Conditions: traumatisch hersenletsel; Chronic Subdural Hematomas - Traumatic Brain Injury; 10007963

• Registration Number: NL-OMON42525
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

* 18 years.
Mentally competent.
Informed consent.
CSDH as a consequence of traumatic brain injury (TBI).
Month of incidence of TBI is known.

Exclusion Criteria

< 18 years.
Not mentally competent.
CSDH not as a consequence of TBI.
Unknown time of incidence of TBI.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The concentration of 6 biomarkers (proteins) in the serum of the CSDH will be<br /><br>measured with an immunosorbent assay (ELISA) in order to determine the age of<br /><br>the CSDH.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Subsequently, the CSDH will be examined with reflection spectroscopy in order<br /><br>to measure the amount of hemoglobine derivatives in the CSDH.<br /><br></p><br>