Measurement of the Metabolome in Melanoma Patients Using NMR Spectroscopy and Gas Chromatography.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 3,000
- 试验地点
- 1
- 主要终点
- Differences in metabolite concentrations
研究概览
简要总结
Prospective, single-centre study with the central question of how the metabolome from blood samples, different body fluids and tissues between patients patients with malignant melanoma in different tumour tumour stages and healthy patients and whether this is suitable for early detection of initial diagnosis, recurrence or stage shift at an early stage.
The biosamples are collected in the BioBank Dresden and used for the NMR and LC-MS analyses described here. It is planned to use the biosamples for further analyses.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Current or past history of melanoma
- •Ongoing therapy or tumour aftercare at the Skin Cancer Centre at Dresden University Hospital
排除标准
- •Refusal to participate in the study
- •Lack of capacity to consent
结局指标
主要结局
Differences in metabolite concentrations
时间窗: through study completion, an average of 3 years
Metabolite concentrations are measured by NMR spectroscopy and gas chromatography and compared between different subgroups.
次要结局
未报告次要终点
研究者
Frank Friedrich Gellrich
Senior Physician in Dermatology and Medical Tumor Therapy, Principal Investigator, MD
University Hospital Carl Gustav Carus