Contact Lenses and Infiltrative Keratitis

Not Applicable

Completed

• Conditions: Keratitis

• Registration Number: NCT02186431
• Lead Sponsor: State University of New York College of Optometry

Brief Summary

To quantify and compare baseline tear proteins and ocular response in contact lens wearers with a history of corneal infiltrative events, to those without a history of complications. This will be accomplished via measurement of select anti-inflammatory tear proteins before, during and after contact lens wear.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-07
• Study First Submitted: 2014-07-07
• Study First Submitted QC: 2014-07-07
• Study First Posted: 2014-07-10
• Primary Completion: 2016-05
• Study Completion: 2016-05
• Status Verified: 2016-07
• Last Update Submitted: 2016-07-08
• Last Update Posted: 2016-07-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• Soft contact lens wearers
• Healthy (control), or with history of infiltrative keratitis (case)
• Has a wearable pair of glasses
• Refractive error between +8.00 D and -12.00 D, with less than 1.50 D of astigmatism

Exclusion Criteria

• Smoker
• Pregnant or nursing
• Systemic disease that would effect tear proteins
• Punctal plugs
• Use of eye drops in the last week

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Tear protein levels	After 4-6 hours of daily wear and after one night extended wear

Trial Locations

Locations (1)

SUNY College of Optometry, Clinical Vision Research Center; 🇺🇸 New York, New York, United States